GSE88779: Mouse Pancreatic Islet Maturation Time Series

Gene Expression Data Explorer
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GROUP CONDITION SAMPLES
Islets: FACS-purified beta cells
GSM2345467 GSM2345468 GSM2345469 GSM2345470
GSM2345459 GSM2345460
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Description

Submission Date: Oct 14, 2016

Summary: Beta cells are the sole source of insulin in our body, yet we do not understand how they mature into fully functional, glucose-responsive beta cells. We generated transcriptomes of FACS-purified beta cells using the Ins1-H2b-mCherry reporter line (Jax # 028589) at different peri- and postnatal maturation stages. This enables a systematic comparison across thousands of genes as beta cells mature.

GEO Accession ID: GSE88779

PMID: 28380380

Description

Submission Date: Oct 14, 2016

Summary: Beta cells are the sole source of insulin in our body, yet we do not understand how they mature into fully functional, glucose-responsive beta cells. We generated transcriptomes of FACS-purified beta cells using the Ins1-H2b-mCherry reporter line (Jax # 028589) at different peri- and postnatal maturation stages. This enables a systematic comparison across thousands of genes as beta cells mature.

GEO Accession ID: GSE88779

PMID: 28380380

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Precomputed Differential Gene Expression

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Differential Gene Expression Analysis
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Bulk RNA-seq Appyter

This pipeline enables you to analyze and visualize your bulk RNA sequencing datasets with an array of downstream analysis and visualization tools. The pipeline includes: PCA analysis, Clustergrammer interactive heatmap, library size analysis, differential gene expression analysis, enrichment analysis, and L1000 small molecule search.