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Raw gene Expression data is sourced from GEO, and the appropriate db package for mapping probes to gene symbols was sourced from the Bioconductor AnnotationData packages.
You can read more about microarray data here.
Select conditions below to toggle them from the plot:
| GROUP | CONDITION | SAMPLES |
|---|---|---|
| C57BL/6 mice, age 15 months |
GSM1816404 GSM1816405 GSM1816406
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|
|
GSM1816399 GSM1816400 GSM1816401 GSM1816402 GSM1816403
|
||
| C57BL/6 mice, age 3 months |
GSM1816394 GSM1816395 GSM1816396 GSM1816397 GSM1816398
|
|
|
GSM1816389 GSM1816390 GSM1816391 GSM1816392 GSM1816393
|
Submission Date: Jul 09, 2015
Summary: We found that deleting Pten in Albumin expressing cells results in liver steatosis as early as 1 month of age. The mice develop hyperplasia and tumor phenotypes starting at 7-8 months of age. At 12 months and beyond, all mice develope spontanous liver tumors of mixed lineage phenotypes dihydrocollidine (DDC) shows that the primary effect of AKT2 loss is attenuation of hepatic injury and not inhibition of progenitor cell proliferation in response to injury.
GEO Accession ID: GSE70681
PMID: No Pubmed ID
Submission Date: Jul 09, 2015
Summary: We found that deleting Pten in Albumin expressing cells results in liver steatosis as early as 1 month of age. The mice develop hyperplasia and tumor phenotypes starting at 7-8 months of age. At 12 months and beyond, all mice develope spontanous liver tumors of mixed lineage phenotypes dihydrocollidine (DDC) shows that the primary effect of AKT2 loss is attenuation of hepatic injury and not inhibition of progenitor cell proliferation in response to injury.
GEO Accession ID: GSE70681
PMID: No Pubmed ID
Visualize Samples
Visualizations are precomputed using the Python package scanpy on the top 5000 most variable genes.
Precomputed Differential Gene Expression
Differential expression signatures are automatically computed using the limma R package.
More options for differential expression are available to compute below.
Signatures:
Select conditions:
Control Condition
Perturbation Condition
Only conditions with at least 1 replicate are available to select
Differential expression signatures can be computed using DESeq2 or characteristic direction.