Raw gene Expression data is sourced from GEO, and the appropriate db package for mapping probes to gene symbols was sourced from the Bioconductor AnnotationData packages.
You can read more about microarray data here.
Select conditions below to toggle them from the plot:
| GROUP | CONDITION | SAMPLES |
|---|---|---|
| liver |
GSM1602122 GSM1602123 GSM1602124
|
|
|
GSM1602125 GSM1602126 GSM1602127
|
Submission Date: Feb 04, 2015
Summary: Control and Liver Insulin Receptor KO mice (LIRKO) were sacrificed in the non-fasted state. RNA was prepared from liver samples and subjected to expression microarray analysis
Each array was hybridized with sample derived from 2-3 mice of the same genotype.
GEO Accession ID: GSE65624
PMID: 25849138
Submission Date: Feb 04, 2015
Summary: Control and Liver Insulin Receptor KO mice (LIRKO) were sacrificed in the non-fasted state. RNA was prepared from liver samples and subjected to expression microarray analysis
Each array was hybridized with sample derived from 2-3 mice of the same genotype.
GEO Accession ID: GSE65624
PMID: 25849138
Visualizations are precomputed using the Python package scanpy on the top 5000 most variable genes.
Differential expression signatures are automatically computed using the limma R package.
More options for differential expression are available to compute below.
Signatures:
Control Condition
Perturbation Condition
Only conditions with at least 1 replicate are available to select
Differential expression signatures can be computed using DESeq2 or characteristic direction.