GSE161355: Type 2 Diabetes Mellitus is Associated with Transcriptome Alterations in Cortical Neurones and Associated Neurovascular Unit Cells in the Ageing Brain

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GROUP CONDITION SAMPLES
Astrocyte
GSM4905218 GSM4905219 GSM4905220 GSM4905221 GSM4905222
GSM4905223 GSM4905224 GSM4905225 GSM4905226 GSM4905227 GSM4905228
Endothelial
GSM4905229 GSM4905230 GSM4905231 GSM4905232
GSM4905233 GSM4905234 GSM4905235 GSM4905236 GSM4905237 GSM4905238 GSM4905239
Neurone
GSM4905240 GSM4905241 GSM4905242 GSM4905243 GSM4905244
GSM4905245 GSM4905246 GSM4905247 GSM4905248 GSM4905249 GSM4905250
Description

Submission Date: Nov 12, 2020

Summary: Type 2 diabetes mellitus (T2D), characterised by peripheral insulin resistance, is a risk factor for dementia. In addition to its contribution to small and large vessel disease, T2D may directly damage cells of the brain neurovascular unit. In this study, we investigated the transcriptomic changes in cortical neurones, and associated astrocytes and endothelial cells of the neurovascular unit, in the ageing brain

GEO Accession ID: GSE161355

PMID: 33407907

Description

Submission Date: Nov 12, 2020

Summary: Type 2 diabetes mellitus (T2D), characterised by peripheral insulin resistance, is a risk factor for dementia. In addition to its contribution to small and large vessel disease, T2D may directly damage cells of the brain neurovascular unit. In this study, we investigated the transcriptomic changes in cortical neurones, and associated astrocytes and endothelial cells of the neurovascular unit, in the ageing brain

GEO Accession ID: GSE161355

PMID: 33407907

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