GSE161355: Type 2 Diabetes Mellitus is Associated with Transcriptome Alterations in Cortical Neurones and Associated Neurovascular Unit Cells in the Ageing Brain

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GROUP CONDITION SAMPLES
Human Neurone, astrocyte, and endothelial cell-enriched RNA
GSM4905245 GSM4905246 GSM4905247 GSM4905248 GSM4905249 GSM4905250
GSM4905240 GSM4905241 GSM4905242 GSM4905243 GSM4905244
Description

Submission Date: Nov 12, 2020

Summary: Type 2 diabetes mellitus (T2D), characterised by peripheral insulin resistance, is a risk factor for dementia. In addition to its contribution to small and large vessel disease, T2D may directly damage cells of the brain neurovascular unit. In this study, we investigated the transcriptomic changes in cortical neurones, and associated astrocytes and endothelial cells of the neurovascular unit, in the ageing brain

GEO Accession ID: GSE161355

PMID: 33407907

Description

Submission Date: Nov 12, 2020

Summary: Type 2 diabetes mellitus (T2D), characterised by peripheral insulin resistance, is a risk factor for dementia. In addition to its contribution to small and large vessel disease, T2D may directly damage cells of the brain neurovascular unit. In this study, we investigated the transcriptomic changes in cortical neurones, and associated astrocytes and endothelial cells of the neurovascular unit, in the ageing brain

GEO Accession ID: GSE161355

PMID: 33407907

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