Select conditions below to toggle them from the plot:
GROUP | CONDITION | SAMPLES |
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gluteal adipose progenitor cells |
GSM4495690 GSM4495692 GSM4495694 GSM4495696 GSM4495698 GSM4495700
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GSM4495689 GSM4495691 GSM4495693 GSM4495695 GSM4495697 GSM4495699
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subcutaneous abdominal adipose progenitor cells |
GSM4495678 GSM4495680 GSM4495682 GSM4495684 GSM4495686 GSM4495688
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GSM4495677 GSM4495679 GSM4495681 GSM4495683 GSM4495685 GSM4495687
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Submission Date: Apr 24, 2020
Summary: GWAS studies and our own work have identified RSPO3 as a gene modulating human body fat distribution. The GWAS signal at RSPO3 is coincident with an eQTL in mature adipocytes. To assess the effects of RSPO3 on abdominal and gluteal adipocyte biology, we undertook inducible RSPO3-knockdown in in vitro differentiated immortalized human abdominal and gluteal adipocyte cell lines (DFAT cells).
GEO Accession ID: GSE149294
PMID: 32493999
Submission Date: Apr 24, 2020
Summary: GWAS studies and our own work have identified RSPO3 as a gene modulating human body fat distribution. The GWAS signal at RSPO3 is coincident with an eQTL in mature adipocytes. To assess the effects of RSPO3 on abdominal and gluteal adipocyte biology, we undertook inducible RSPO3-knockdown in in vitro differentiated immortalized human abdominal and gluteal adipocyte cell lines (DFAT cells).
GEO Accession ID: GSE149294
PMID: 32493999
Signatures:
Control Condition
Perturbation Condition
Only conditions with at least 1 replicate are available to select
This pipeline enables you to analyze and visualize your bulk RNA sequencing datasets with an array of downstream analysis and visualization tools. The pipeline includes: PCA analysis, Clustergrammer interactive heatmap, library size analysis, differential gene expression analysis, enrichment analysis, and L1000 small molecule search.