GSE145070: RNA-seq analysis of Control and BSCL2-deleted mature brown adipose tissue in mice

Gene Expression Data Explorer
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GROUP CONDITION SAMPLES
Brown Adipose Tissue
GSM4305739 GSM4305740 GSM4305741
GSM4305742 GSM4305743 GSM4305744
Description

Submission Date: Feb 10, 2020

Summary: Next generation sequencing was used to compare transcriptome profiling in brown adipose tissue from Ctrl and BKO mice with mature brown adipose tissue specific deletion of BSCL2. Using an optimized data analysis workflow, we identified 13,525 transcripts in brown adipose tissue. 243 genes were differentially expressed with a fold change ≥1.5 and Padj value <0.05. Only 99 genes showed differential expression between the Ctrl and BKO brown fat, with a fold change ≥2.0 and Padj value <0.05. Results provide insights into the processes and signaling pathways BSCL2-mediated in brown adipose tissue.

GEO Accession ID: GSE145070

PMID: 32246911

Description

Submission Date: Feb 10, 2020

Summary: Next generation sequencing was used to compare transcriptome profiling in brown adipose tissue from Ctrl and BKO mice with mature brown adipose tissue specific deletion of BSCL2. Using an optimized data analysis workflow, we identified 13,525 transcripts in brown adipose tissue. 243 genes were differentially expressed with a fold change ≥1.5 and Padj value <0.05. Only 99 genes showed differential expression between the Ctrl and BKO brown fat, with a fold change ≥2.0 and Padj value <0.05. Results provide insights into the processes and signaling pathways BSCL2-mediated in brown adipose tissue.

GEO Accession ID: GSE145070

PMID: 32246911

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Precomputed Differential Gene Expression

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Differential Gene Expression Analysis
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Bulk RNA-seq Appyter

This pipeline enables you to analyze and visualize your bulk RNA sequencing datasets with an array of downstream analysis and visualization tools. The pipeline includes: PCA analysis, Clustergrammer interactive heatmap, library size analysis, differential gene expression analysis, enrichment analysis, and L1000 small molecule search.