Raw gene Expression data is sourced from GEO, and the appropriate db package for mapping probes to gene symbols was sourced from the Bioconductor AnnotationData packages.
You can read more about microarray data here.
Select conditions below to toggle them from the plot:
| GROUP | CONDITION | SAMPLES |
|---|---|---|
| Brown Adipose Tissue (BAT) |
GSM4191296 GSM4191298 GSM4191299 GSM4191301
|
|
|
GSM4191290 GSM4191291 GSM4191292 GSM4191293 GSM4191294 GSM4191295
|
Submission Date: Nov 25, 2019
Summary: DBA/2N Ahsg -/- mice suffer from sever soft tissue calcification. Gene expression in brown adipose tissue isolated from the pelvic region of 6 week old mice was analyzed, representing early stage calcification.
Evaluation of the gene expression pattern was performed to provide insights into the mechanisms associated with soft tissue calcification.
GEO Accession ID: GSE140953
PMID: No Pubmed ID
Submission Date: Nov 25, 2019
Summary: DBA/2N Ahsg -/- mice suffer from sever soft tissue calcification. Gene expression in brown adipose tissue isolated from the pelvic region of 6 week old mice was analyzed, representing early stage calcification.
Evaluation of the gene expression pattern was performed to provide insights into the mechanisms associated with soft tissue calcification.
GEO Accession ID: GSE140953
PMID: No Pubmed ID
Visualizations are precomputed using the Python package scanpy on the top 5000 most variable genes.
Differential expression signatures are automatically computed using the limma R package.
More options for differential expression are available to compute below.
Signatures:
Control Condition
Perturbation Condition
Only conditions with at least 1 replicate are available to select
Differential expression signatures can be computed using DESeq2 or characteristic direction.