Microarray Data Explorer
Info Raw gene Expression data is sourced from GEO, and the appropriate db package for mapping probes to gene symbols was sourced from the Bioconductor AnnotationData packages. You can read more about microarray data here.
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GROUP CONDITION SAMPLES
2D Monolayer
GSM4121417 GSM4121418 GSM4121419
GSM4121420 GSM4121421 GSM4121422
3D reconstituted basement membrane (rBM)
GSM4121423 GSM4121424 GSM4121425
GSM4121426 GSM4121427 GSM4121428
Description

Submission Date: Oct 15, 2019

Summary: The series represent gene expression profiles of HMT3522 S1 mammary epithelial cells cultured as 2D monolayers or in 3D reconstituted basement membrane (rBM) and treated with the death ligand TRAIL. Keywords: Genetic modification; response to death induction

GEO Accession ID: GSE138900

PMID: No Pubmed ID

Description

Submission Date: Oct 15, 2019

Summary: The series represent gene expression profiles of HMT3522 S1 mammary epithelial cells cultured as 2D monolayers or in 3D reconstituted basement membrane (rBM) and treated with the death ligand TRAIL. Keywords: Genetic modification; response to death induction

GEO Accession ID: GSE138900

PMID: No Pubmed ID

Visualize Samples

Info Visualizations are precomputed using the Python package scanpy on the top 5000 most variable genes.

Precomputed Differential Gene Expression

Info Differential expression signatures are automatically computed using the limma R package. More options for differential expression are available to compute below.

Signatures:

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Control Condition

Perturbation Condition

Only conditions with at least 1 replicate are available to select

Differential Gene Expression Analysis
Info Differential expression signatures can be computed using DESeq2 or characteristic direction.
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