GSE135391: Transcriptome analysis of brown fat in young or old mice in cold exposure

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GROUP CONDITION SAMPLES
coldroom (4°c)
GSM4007543
coldroom (4°c)
GSM4007542 GSM4007550 GSM4007551 GSM4007558
GSM4007546 GSM4007547 GSM4007554 GSM4007555
room temp (24°c)
GSM4007544 GSM4007545 GSM4007552 GSM4007553 GSM4007559
GSM4007548 GSM4007549 GSM4007556 GSM4007557 GSM4007560
Description

Submission Date: Aug 05, 2019

Summary: Purpose: We investigated the transcriptomic change in brown fat of young and old mice (wild type) through high-throughput RNA-sequencing (RNA-Seq) analysis when the mice were exposed to cold room or room temperatur.

Methods: We prepared 10 of young (3 months) mice and 9 of old (24 months) mice, and kept them in cold room (4°c) or room temperature (24°c) for 24 hours. Then, we sacrified mice and extracted RNA from brown fat tissue (BAT) for RNA-seq experiment.

Results: BAT of Young mice showed increased carbohydrate metabolism and glycolytic flux during cold exposure

Conclusions: The thermogenesis function of BAT is accelerated on cold exposure.

GEO Accession ID: GSE135391

PMID: 32795388

Description

Submission Date: Aug 05, 2019

Summary: Purpose: We investigated the transcriptomic change in brown fat of young and old mice (wild type) through high-throughput RNA-sequencing (RNA-Seq) analysis when the mice were exposed to cold room or room temperatur.

Methods: We prepared 10 of young (3 months) mice and 9 of old (24 months) mice, and kept them in cold room (4°c) or room temperature (24°c) for 24 hours. Then, we sacrified mice and extracted RNA from brown fat tissue (BAT) for RNA-seq experiment.

Results: BAT of Young mice showed increased carbohydrate metabolism and glycolytic flux during cold exposure

Conclusions: The thermogenesis function of BAT is accelerated on cold exposure.

GEO Accession ID: GSE135391

PMID: 32795388

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