GSE124774: RNA-seq of diabetic or non-diabetic murine bone marrow derived macrophages (BMDM)

Gene Expression Data Explorer
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GROUP CONDITION SAMPLES
Diabetic mice
GSM3553687 GSM3553688 GSM3553691 GSM3553692 GSM3553695 GSM3553696
GSM3553699 GSM3553700 GSM3553703 GSM3553704 GSM3553707 GSM3553708
Wildtype Healthy Control
GSM3553689 GSM3553690 GSM3553693 GSM3553694 GSM3553697 GSM3553698
GSM3553701 GSM3553702 GSM3553705 GSM3553706 GSM3553709 GSM3553710
Description

Submission Date: Jan 07, 2019

Summary: The aim of this study was to interrogate whether BMDM basal or pro-inflammatory stimulated gene expression is altered by diabetes and persists despite in vitro glucose normalisation. Unstimulated BMDM from diabetic mice differentially express 632 genes (324 increased and 308 downregulated) compared to unstimulated control BMDM; this increases to 1,348 genes (802 increased and 546 decreased) upon stimulation (FDR<0.05, FC>1.5).

GEO Accession ID: GSE124774

PMID: No Pubmed ID

Description

Submission Date: Jan 07, 2019

Summary: The aim of this study was to interrogate whether BMDM basal or pro-inflammatory stimulated gene expression is altered by diabetes and persists despite in vitro glucose normalisation. Unstimulated BMDM from diabetic mice differentially express 632 genes (324 increased and 308 downregulated) compared to unstimulated control BMDM; this increases to 1,348 genes (802 increased and 546 decreased) upon stimulation (FDR<0.05, FC>1.5).

GEO Accession ID: GSE124774

PMID: No Pubmed ID

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Precomputed Differential Gene Expression

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Differential Gene Expression Analysis
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Bulk RNA-seq Appyter

This pipeline enables you to analyze and visualize your bulk RNA sequencing datasets with an array of downstream analysis and visualization tools. The pipeline includes: PCA analysis, Clustergrammer interactive heatmap, library size analysis, differential gene expression analysis, enrichment analysis, and L1000 small molecule search.