Select conditions below to toggle them from the plot:
GROUP | CONDITION | SAMPLES |
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Left ventricular |
GSM309962 GSM309963 GSM309964 GSM309965
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GSM309966 GSM309967 GSM309968 GSM309969
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GSM309958 GSM309959 GSM309960 GSM309961
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GSM309970 GSM309971 GSM309972 GSM309973
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Submission Date: Aug 05, 2008
Summary: Findings suggest that PPARalpha plays a decisive role in the development of hypertrophy, affecting the functional outcome of the heart. Unfortunately, information on the nature of PPARalpha-dependent processes in cardiac hypertrophy is fragmentary and incomplete.
The primary aim of this study was to identify the processes and signaling pathways regulated by PPARalpha in hearts challenged by a chronic pressure overload by means of whole genome transcriptomic analysis. Second, we wanted to gain insight how PPARalpha modulates the identified processes, e.g. by trans-activation or by trans-repression.
Keywords: 28 days of TAC
GEO Accession ID: GSE12337
PMID: 18812456
Submission Date: Aug 05, 2008
Summary: Findings suggest that PPARalpha plays a decisive role in the development of hypertrophy, affecting the functional outcome of the heart. Unfortunately, information on the nature of PPARalpha-dependent processes in cardiac hypertrophy is fragmentary and incomplete.
The primary aim of this study was to identify the processes and signaling pathways regulated by PPARalpha in hearts challenged by a chronic pressure overload by means of whole genome transcriptomic analysis. Second, we wanted to gain insight how PPARalpha modulates the identified processes, e.g. by trans-activation or by trans-repression.
Keywords: 28 days of TAC
GEO Accession ID: GSE12337
PMID: 18812456
Signatures:
Control Condition
Perturbation Condition
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